avanti polar lipids/2-arachidonoyl glycerol/870450O-5mg
商品编号:
870450O-5mg
品牌:
Avanti
市场价:
¥2848.00
美元价:
2136.00
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
2-AG
2-arachidonoyl glycerol
2-Arachidonoylglycerol (2-AG), is an endocannabinoid, an endogenous agonist of the CB1 receptor. 2-AG, unlike anandamide, is present at relatively high levels in the central nervous system; it is the most abundant molecular species of monoacylglycerol found in mouse and rat brain (~5-10 nmol/g tissue). Detection of 2-AG in brain tissue is complicated by the relative ease of its isomerization to 1-AG during standard lipid extraction conditions. Unlike anandamide, formation of 2-AG is calcium-dependent and is mediated by the activities of phospholipase C (PLC) and diacylglycerol lipase (DAGL). 2-AG acts as a full agonist at the CB1 receptor. At a concentration of 0.3 nM, 2-AG induces a rapid, transient increase in intracellular free calcium in NG108-15 neuroblastoma X glioma cells through a CB1 receptor-dependent mechanism. 2-AG is hydrolyzed in vitro by monoacylglycerol lipase (MAGL), fatty acid amide hydrolase (FAAH), and the uncharacterized serine hydrolase enzymes ABHD6 and ABHD12. The exact contribution of each of these enzymes to the termination of 2-AG signaling in vivo is unknown, though it is estimated that MAGL is responsible for ~85% of this activity.
Note: This product is supplied in a PTFE vial and should not be stored in glass.
品牌介绍
Avanti Polar Lipids
阿凡提极地脂质公司,有着50年的历史,创造了最高纯度的脂类产品。我们对高质量和独特的产品的热情只会被我们在市场上的良好声誉所超越。
Since its spartan beginnings in a 900 square foot rented laboratory space, Avanti has established a 25 acre manufacturing campus comprised of 11 buildings which house our manufacturing, formulation, analytical, and administrative units. Operations were moved to the current site in Alabaster, Alabama, in 1990, and we have continued to expand our capabilities and attract talented personnel to develop new and innovative products. With over 120 employees diligently working to provide high quality revolutionary lipid products, we have successfully grown our product offering to well over 2000 unique lipids, antibodies, and lipid research tools while maintaining the founding vision established by Dr. Shaw in 1967. Quite an accomplishment considering we started with a catalog containing only a handful of lipids isolated from plant and animal sources.
品牌
货号
名称
规格
Avanti Polar Lipids
860853
16:0 Azido Coenzyme A
1mg
Avanti Polar Lipids
900415
Oleic Acid (18-azido)
5mg 25mg
Avanti Polar Lipids
900414
16:0(alkyne)-18:1 PE
1mg 5mg
Avanti Polar Lipids
900413
16:0(alkyne)-18:1 PC
1mg 5mg
Avanti Polar Lipids
860831
C6(6-azido) Ceramide
5mg
Avanti Polar Lipids
860832
C6(6-azido) LacCer
5mg
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860833
C6(6-azido) GalCer
5mg
Avanti Polar Lipids
860834
C6(6-azido) GluCer
5mg
Avanti Polar Lipids
900600
PhotoClick Sphingosine
100ug 250ug
Avanti Polar Lipids
810340
Click PI(4,5)P2-azido
100ug
Avanti Polar Lipids
900400
Palmitic acid (15-yne)
1mg 5mg
Avanti Polar Lipids
900404
pacFA Ceramide
1mg
Avanti Polar Lipids
900405
pacFA GlcCer
1mg
Avanti Polar Lipids
900406
pacFA GalCer
1mg
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900407
16:0-pacFA PC
1mg
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阳离子脂质(转染)
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