700147 | PhotoClick Cholesterol
Hex-5"-ynyl 3ß-hydroxy-6-diazirinyl-5α-cholan-24-oate
PhotoClick Cholesterol
Hex-5"-ynyl 3ß-hydroxy-6-diazirinyl-5α-cholan-24-oate
PhotoClick Cholesterol is a clickable, photoreactive sterol probe for use in combination with quantitative mass spectrometry to globally map cholesterol-protein interactions directly in living cells. In addition to the UV-activatable cross-linking diazirine group that reacts with proteins, the sterol contains an alkyne group for incorporation of reporter and affinity tags through click-chemistry.
- ChemDraw File
- 3D Structure
- Structure
- Safety Data Sheet
Chauhan N, Sere YY, Sokol AM, Graumann J, Menon AK. A PhotoClick cholesterol-based quantitative proteomics screen for cytoplasmic sterol binding proteins in Saccharomyces cerevisiae. Yeast. 2019 Nov 22. doi: 10.1002/yea.3448. [Epub ahead of print]
PubMed ID: 31758572Hulce JJ, Cognetta AB, Niphakis MJ, Tully SE, Cravatt BF. Proteome-wide mapping of cholesterol-interacting proteins in mammalian cells. Nat Methods. 2013 Mar;10(3):259-64. doi: 10.1038/nmeth.2368. Epub 2013 Feb 10. PMID: 23396283; PMCID: PMC3601559.
PubMed ID: 23396283- Certificate of Analysis(Lot No. 700147P-100UG-A-010and 5211PDA010)
- Certificate of Analysis(Lot No. 700147P-250UG-010and 5211PEG010)
- Certificate of Analysis(Lot No. 700147P-250UG-A-010and 5211PEA010)
- Certificate of Analysis(Lot No. 700147P-250UG-B-010and 5211PEB010)
- Certificate of Analysis(Lot No. 700147P-100UG-A-010and 5211PDA010)
- Certificate of Analysis(Lot No. 700147P-100UG-C-010and 5211PDC010)
- Certificate of Analysis(Lot No. 700147P-250UG-D-010and 5211PED010)