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当前位置: 首页 > 产品中心 > Sterols > avanti极性脂质/15十六烷酸/1 x 1mg/900400P-1mg
商品详细avanti极性脂质/15十六烷酸/1 x 1mg/900400P-1mg
avanti极性脂质/15十六烷酸/1 x 1mg/900400P-1mg
avanti极性脂质/15十六烷酸/1 x 1mg/900400P-1mg
商品编号: 900400P-1mg
品牌: Avanti
市场价: ¥2734.80
美元价: 2040.00
产地: 美国(厂家直采)
公司:
产品分类: 固醇类
公司分类: Sterols
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

900400 | Palmitic acid (15-yne)

15-hexadecynoic acid

Palmitic acid (15-yne)
Info

Palmitic acid (15-yne)

15-hexadecynoic acid

Alkynyl palmitic acid (aPA) is a modified palmitic acid with an ω-terminal alkyne. The terminal alkyne group can be used in a highly specific linking reaction with azide-containing reagents, known as ‘click chemistry’. The use of aPA in isolating palmitoylated proteins has been described (see References).

Data
Hygroscopic
No
Light Sensitive
No
Molecular Formula
C16H28O2
Percent Composition
C 76.14%, H 11.18%, O 12.68%
Purity
>99%
Stability
1 Years
Storage Temperature
-20°C
CAS Number
99208-90-9 CAS Registry Number is a Registered Trademark of the American Chemical Society
FormulaWeight
252.392
Exact Mass
252.209
Synonyms
aPA
Downloads
  • ChemDraw File
  • 3D Structure
  • Structure
  • Safety Data Sheet
References

Ticho AL, Malhotra P, Manzella CR, Dudeja PK, Saksena S, Gill RK, Alrefai WA. S-Acylation modulates the function of the apical sodium-dependent bile acid transporter in human cells. J Biol Chem. 2020 Feb 18:jbc.RA119.011032. doi: 10.1074/jbc.RA119.011032. Epub ahead of print. PMID: 32071081.

PubMed ID: 32071081

Tallman KA, Armstrong MD, Milne SB, Marnett LJ, Brown HA, Porter NA. Cobalt carbonyl complexes as probes for alkyne-tagged lipids. J Lipid Res. 2013 Mar;54(3):859-68. doi: 10.1194/jlr.D033332. Epub 2013 Jan 10. PMID: 23307946; PMCID: PMC3617960.

PubMed ID: 23307946

Milne SB, Tallman KA, Serwa R, Rouzer CA, Armstrong MD, Marnett LJ, Lukehart CM, Porter NA, Brown HA. Capture and release of alkyne-derivatized glycerophospholipids using cobalt chemistry. Nat Chem Biol. 2010 Mar;6(3):205-207. doi: 10.1038/nchembio.311. Epub 2010 Jan 24. PMID: 20098428; PMCID: PMC2822082.

PubMed ID: 20098428

Jiang H, Khan S, Wang Y, Charron G, He B, Sebastian C, Du J, Kim R, Ge E, Mostoslavsky R, Hang HC, Hao Q, Lin H. SIRT6 regulates TNF-α secretion through hydrolysis of long-chain fatty acyl lysine. Nature. 2013 Apr 4;496(7443):110-3. doi: 10.1038/nature12038. PMID: 23552949; PMCID: PMC3635073.

PubMed ID: 23552949

Thiele C, Papan C, Hoelper D, Kusserow K, Gaebler A, Schoene M, Piotrowitz K, Lohmann D, Spandl J, Stevanovic A, Shevchenko A, Kuerschner L. Tracing fatty acid metabolism by click chemistry. ACS Chem Biol. 2012 Dec 21;7(12):2004-11. doi: 10.1021/cb300414v. Epub 2012 Oct 2. PMID: 22999348.

PubMed ID: 22999348

Gao X, Arenas-Ramirez N, Scales SJ, Hannoush RN. Membrane targeting of palmitoylated Wnt and Hedgehog revealed by chemical probes. FEBS Lett. 2011 Aug 4;585(15):2501-6. doi: 10.1016/j.febslet.2011.06.033. Epub 2011 Jul 2. PMID: 21740904.

PubMed ID: 21740904

Yap MC, Kostiuk MA, Martin DD, Perinpanayagam MA, Hak PG, Siddam A, Majjigapu JR, Rajaiah G, Keller BO, Prescher JA, Wu P, Bertozzi CR, Falck JR, Berthiaume LG. Rapid and selective detection of fatty acylated proteins using omega-alkynyl-fatty acids and click chemistry. J Lipid Res. 2010 Jun;51(6):1566-80. doi: 10.1194/jlr.D002790. Epub 2009 Dec 21. PMID: 20028662; PMCID: PMC3035521.

PubMed ID: 20028662

Martin BR, Cravatt BF. Large-scale profiling of protein palmitoylation in mammalian cells. Nat Methods. 2009 Feb;6(2):135-8. doi: 10.1038/nmeth.1293. Epub 2009 Jan 11. PMID: 19137006; PMCID: PMC2775068.

PubMed ID: 19137006
Certificates of Analysis
  • Certificate of Analysis(Lot No. 900400P-1MG-A-010and 6377PGA010)
  • Certificate of Analysis(Lot No. 900400P-5MG-A-010and 6377PHA010)
  • Certificate of Analysis(Lot No. 900400P-1MG-B-010and 6377PGB010)
  • Certificate of Analysis(Lot No. 900400P-1MG-B-010and 6377PGB010)
  • Certificate of Analysis(Lot No. 900400P-5MG-C-010and 6377PHC010)
  • Certificate of Analysis(Lot No. 900400P-1MG-C-010and 6377PGC010)
  • Certificate of Analysis(Lot No. 900400P-5MG-D-010and 6377PHD010)
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品牌介绍
Avanti Polar Lipids 阿凡提极地脂质公司,有着50年的历史,创造了最高纯度的脂类产品。我们对高质量和独特的产品的热情只会被我们在市场上的良好声誉所超越。 Since its spartan beginnings in a 900 square foot rented laboratory space, Avanti has established a 25 acre manufacturing campus comprised of 11 buildings which house our manufacturing, formulation, analytical, and administrative units. Operations were moved to the current site in Alabaster, Alabama, in 1990, and we have continued to expand our capabilities and attract talented personnel to develop new and innovative products. With over 120 employees diligently working to provide high quality revolutionary lipid products, we have successfully grown our product offering to well over 2000 unique lipids, antibodies, and lipid research tools while maintaining the founding vision established by Dr. Shaw in 1967. Quite an accomplishment considering we started with a catalog containing only a handful of lipids isolated from plant and animal sources. 品牌 货号 名称 规格 Avanti Polar Lipids 860853 16:0 Azido Coenzyme A 1mg Avanti Polar Lipids 900415  Oleic Acid (18-azido) 5mg 25mg Avanti Polar Lipids 900414 16:0(alkyne)-18:1 PE 1mg 5mg Avanti Polar Lipids 900413 16:0(alkyne)-18:1 PC 1mg 5mg Avanti Polar Lipids 860831  C6(6-azido) Ceramide 5mg Avanti Polar Lipids 860832 C6(6-azido) LacCer 5mg Avanti Polar Lipids 860833  C6(6-azido) GalCer 5mg Avanti Polar Lipids 860834 C6(6-azido) GluCer 5mg Avanti Polar Lipids 900600 PhotoClick Sphingosine 100ug 250ug Avanti Polar Lipids 810340 Click PI(4,5)P2-azido 100ug Avanti Polar Lipids 900400 Palmitic acid (15-yne) 1mg 5mg Avanti Polar Lipids 900404 pacFA Ceramide 1mg Avanti Polar Lipids 900405 pacFA GlcCer 1mg Avanti Polar Lipids 900406 pacFA GalCer 1mg Avanti Polar Lipids 900407 16:0-pacFA PC 1mg